PRP for Shoulder Tendonitis: A Targeted Approach to Easing Pain

Medically Reviewed Reviewed by DR JOHN PRP
This article has been reviewed for medical accuracy by a licensed physician with experience in integrative health.

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Shoulder tendonitis—particularly rotator cuff tendonitis—is a common cause of persistent shoulder pain and limited range of motion. Whether due to repetitive overhead motion, injury, or wear and tear over time, tendonitis can interfere with daily life and make even simple activities uncomfortable.

Platelet-rich plasma (PRP) therapy is gaining attention in Australia as a regenerative option for managing orthopaedic conditions like tendonitis. In this article, we explore how PRP for shoulder tendonitis works, what to expect from the procedure, and how it may complement other rehabilitation strategies.

Understanding Shoulder Tendonitis

Tendonitis refers to inflammation or micro-tears in a tendon—the thick, fibrous cord that connects muscle to bone. In the shoulder, this often affects the rotator cuff tendons (especially the supraspinatus), leading to:

  • Dull, aching pain in the shoulder or upper arm
  • Pain when lifting the arm or reaching overhead
  • Weakness or stiffness
  • Disturbed sleep due to pain at night

Conventional treatments like rest, physiotherapy, and corticosteroid injections may offer temporary relief. However, they don’t always address the underlying tendon degeneration. That’s where regenerative options like PRP may play a role.

How PRP Therapy Works for Shoulder Tendonitis

PRP therapy uses your own blood to stimulate healing in injured tissue. After a small blood draw, your blood is processed in a centrifuge to concentrate the platelets—cells that contain powerful growth factors.

The resulting platelet-rich plasma is then injected directly into the injured tendon under ultrasound guidance. These growth factors are believed to support tissue repair, reduce inflammation, and potentially improve tendon structure over time.

Because PRP is derived from your own blood, the risk of rejection or allergic reaction is extremely low. However, outcomes can vary from person to person and should be considered within a broader treatment plan.

The PRP Injection Procedure

Receiving PRP injections for shoulder tendonitis is a relatively quick outpatient process. Here’s what typically happens:

  1. A small sample of blood is drawn, usually from your arm.
  2. The blood is spun in a centrifuge to isolate the platelet-rich plasma.
  3. The PRP is injected into the affected tendon using ultrasound guidance for precision.
  4. The entire process usually takes less than an hour.

After the injection, you may experience mild swelling, soreness, or a temporary increase in discomfort. This is typically part of the healing response and should subside within a few days.

Who May Benefit from PRP for Shoulder Tendonitis?

PRP therapy may be considered if:

  • You’ve had persistent shoulder pain for more than 6–12 weeks
  • Imaging shows signs of tendon thickening or microtears
  • You’ve already tried rest, physiotherapy, and activity modification
  • You want to avoid or delay surgery

PRP is commonly used for non-tear or partial-thickness rotator cuff injuries. It’s important to have a clear diagnosis before considering the injection.

Combining PRP with Physiotherapy

PRP is not a standalone cure—it works best as part of a broader recovery strategy. Many orthopaedic patients benefit from a physiotherapy program that begins a few days after the injection.

Physiotherapy for rotator cuff tendonitis typically focuses on:

  • Range-of-motion exercises
  • Scapular stability training
  • Gradual strengthening of rotator cuff muscles
  • Postural adjustments to reduce strain on the shoulder

This combined approach supports tissue healing and functional recovery.

Expert Tip

“PRP is most effective when targeted carefully and supported with rehabilitation. In patients with mild to moderate rotator cuff pathology, it can offer a non-surgical alternative that encourages natural tissue repair.”

Key Takeaways

  • PRP therapy may support healing in rotator cuff tendonitis and reduce shoulder pain
  • The injection uses your own blood platelets, minimising the risk of adverse reaction
  • Most patients begin physiotherapy within a week after PRP to aid recovery
  • PRP works best when combined with activity modification and postural retraining
  • A thorough diagnosis is essential to determine if PRP is appropriate for your condition

References

  1. Fitzpatrick J, Bulsara M, Zheng MH. “The effectiveness of platelet-rich plasma in the treatment of tendinopathy: A meta-analysis.” Am J Sports Med. 2017.
  2. Mautner K, et al. “A call for a standard classification system for future biologic research: The rationale for new PRP nomenclature.” PM&R. 2015.
  3. Andia I, Maffulli N. “Platelet-rich plasma for managing pain and inflammation in osteoarthritis.” Nat Rev Rheumatol. 2013.
  4. Kesikburun S, et al. “Platelet-rich plasma injections in the treatment of chronic rotator cuff tendinopathy: a randomized controlled trial.” Am J Sports Med. 2013.
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